Results 101 to 110 of about 443,997 (287)
Analysing Wage Formation in the South African Labour Market: The Role of Bargaining Councils [PDF]
The role of bargaining councils, the central pillar of collective bargaining in South Africa, in the formation of wages is important in the context of high unemployment rates in South Africa.
Carlene van der Westhuizen +2 more
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Early Childhood Councils: Effective Planning Processes for Health Systems Integration [PDF]
, 2011 The Colorado Trust launched its Early Childhood Council Health Integration grant strategy in 2008. Through this effort, the Early Childhood Councils developed strategies to better integrate health practitioners and health care services into their work ...
Elizabeth Bruner, Jennifer Schroeder
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Emergency management on the island of Ireland – Recent cross-border developments
Administration, 2015 Emergency management has developed separately in Northern Ireland and the Republic of Ireland as a result of the differences in the political, legal, organisational and cultural backgrounds that exist in the two jurisdictions.
Joyce Finian, McCaffrey Joan
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
System of the Regional Executive Power in the USSR at a Boundary of the 1920-1930 th Years
Управленческое консультирование, 2018 In the article the condition of executive power in the USSR at the regional level at a boundary of the 1920-1930th on the example of Central Black Earth Region is analyzed.
Alexander Yurievich Saran
doaj
Hungarian Judges’ Attitudes Towards the “Illiberal State”
European Journal of Empirical Legal StudiesThe goal of this paper is to explore the attitudes of Hungarian judges towards the “illiberal democracy” project of Victor Orban - twelve years into its development.
Frans van Dijk, Kamil Jonski
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Patient Experience Journal, 2018 Although the landscape in pediatrics continues to shift and change, one of the keys to our continued success remains the same… it’s about partnership. It’s clear the element of partnership is well woven through our organizations as illustrated by many of
Rachel Biblow, MSW, Sara Toomey
doaj