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Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Measuring the Delivery Costs of Prepurchase Homeownership Education and Counseling [PDF]
In order to understand the roles that public policy and the business and consumer sectors play in paying for homeownership education and counseling, the costs, benefits and beneficiaries of the education and training must be fully accounted for.
Christi Baker, Michael Collins
core
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Comparing Personality Dimensions and coping Strategies in Healthy Individuals and Heart Patients
Introduction: Heart disease is a psycho-physiological disorder that in addition to physical and biological factors, psychological factors such as stressful events, personality traits and coping strategies play an important role in its occurrence and ...
R Rahimi, M Arefi, M Golmohammadian
doaj
Parents' dilemmas and decision making on the outcome of pregnancy after prenatal diagnoses of fetal anomalies [PDF]
During the last decades prenatal screening and diagnostic methods have significantly improved and the number of fetal disorders that can be detected in all stages of pregnancy has increased.
Cvijetić Marija
doaj +1 more source
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
White Counselor Trainees\u27 Racial Identity and Working Alliance Perceptions [PDF]
Racial identity has been theorized to significantly affect cross-racial counseling relationships (Helms, 1984, 1995). This study examined the direct impact of White racial identity of 124 counselor trainees on working alliance formation in a same-racial ...
Alfonso, Vincent+3 more
core +2 more sources
Background: The statistics of extramarital affairs are increasing due to its negative effects in different societies and it is a matter of concern, especially that in backgrounds related to infidelity, extramarital affairs is associated with a decrease ...
azam iamni rad+3 more
doaj
Ethnolinguistic concordance and the receipt of postpartum IUD counseling services in Sri Lanka. [PDF]
CONTEXT: Ethnic and linguistic concordance are important dimensions of the patient-physician relationship, and are linked to health care disparities.
Canning, David+5 more
core +1 more source