Results 121 to 130 of about 1,320,886 (340)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The Effect of Counseling on Self-Esteem and Health-promoting Behaviors in Psychiatric Patients Receiving Electroconvulsive Therapy: A Clinical Trial Study

open access: yesمراقبت پرستاری و مامایی ابن سینا, 2021
Background and Objective: Compared to the general population, patients with psychiatric disorders, especially patients receiving electroconvulsive therapy due to its nature, and lack of psychiatric nursing counseling have worse physical health and lower ...
Parisa Rostami   +2 more
doaj  

GOOD COUNSEL [PDF]

open access: green, 1920
NULL AUTHOR_ID
openalex   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Effectiveness of Group Reality Therapy on Emotion Regulation and Academic Self-efficacy of Female Students

open access: yesSalāmat-i ijtimā̒ī, 2018
Background and Objective: Self-effiacy beliefs are home base and motivation Center in human and related to variety of cognitive and motivational factors such as and emotional regulation.
Mansooreh Ghoreishi, Masoomeh Behboodi
doaj  

Shakespeare & School Counseling [PDF]

open access: yes, 2014
Dr. Abel addresses the use of Shakespeare in school counseling settings.
Abel, Nick R.
core   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

European American Therapist Self-Disclosure in Cross-Cultural Counseling [PDF]

open access: yes, 2006
Eleven European American psychotherapists\u27 use of self-disclosure in cross-cultural counseling was studied using consensual qualitative research. As reasons for self-disclosing, therapists reported the intent to enhance the counseling relationship ...
Burkard, Alan W.   +4 more
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

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