Results 21 to 30 of about 150,237 (223)

Effectiveness of acceptance and commitment group therapy on marital distress, marital conflict and optimism in married women visited the counseling center of Imam Khomeini Relief Foundation in Kermanshah [PDF]

روانشناسی و روانپزشکی شناخت, 2018
Aim: The study aimed at determining the effectiveness of acceptance and commitment group therapy on marital distress, marital conflict, and optimism. Methodology: The study was formed of quasi-experimental design with pretest-posttest and follow-up ...
Ahmad Amani, Omid Isanejad, Elahe Alipour   +2 more
doaj   +1 more source

ChatCounselor: A Large Language Models for Mental Health Support [PDF]

arXiv, 2023
This paper presents ChatCounselor, a large language model (LLM) solution designed to provide mental health support. Unlike generic chatbots, ChatCounselor is distinguished by its foundation in real conversations between consulting clients and professional psychologists, enabling it to possess specialized knowledge and counseling skills in the field of ...
arxiv  

Teaching Behaviour and Well-Being in Students: Development and Concurrent Validity of an Instrument to Measure Student-Reported Teaching Behaviour [PDF]

International Journal of Emotional Education, 2013
Teaching behavior has important implications for students’ emotional well-being. Multiple models suggest students’ perceptions of teaching behaviors are more critical than other measures for predicting well-being, yet student-report instruments that ...
Patrick Pössel, Kathleen Moritz Rudasill, Jill L. Adelson, Annie C. Bjerg, Don T. Wooldridge, Stephanie Winkeljohn Black   +5 more
doaj  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Adaptation, Development, and Validation of the Spiritual Community and Togetherness Scale (SCoTS)

Psychology International
We adapted the SCoTS from the Collegiate Psychological Sense of Community Scale to measure religious/spiritual (R/S) community and belonging among college students.
Christopher R. Dabbs, Carrie L. Winterowd, Elizabeth A. Albright, Tiffany Kolba, Tianna Etes, Bronson K. Snyder, Jeffery Logan Riddle, Kidist A. Beker   +7 more
doaj   +1 more source

Parents' dilemmas and decision making on the outcome of pregnancy after prenatal diagnoses of fetal anomalies [PDF]

Psihološka Istraživanja, 2016
During the last decades prenatal screening and diagnostic methods have significantly improved and the number of fetal disorders that can be detected in all stages of pregnancy has increased.
Cvijetić Marija
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source