Results 81 to 90 of about 1,320,886 (340)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

“Shaping ChatGPT into my Digital Therapist”: A thematic analysis of social media discourse on using generative artificial intelligence for mental health

open access: yesDigital Health
Objective Generative artificial intelligence (genAI) has become popular for the general public to address mental health needs despite the lack of regulatory oversight.
Xiaochen Luo   +5 more
doaj   +1 more source

The Current Status of School Counseling Outcome Research [PDF]

open access: yes, 2005
Wendy McGannon has taken the lead in developing a review and analysis of The Current Status of School Counseling Outcome Research. Some basic information related to the NCLB mandates are reviewed in terms of how they impact the school counseling ...
Carey, Jay   +2 more
core   +1 more source

Effect of Staff Training and Cost Support on Provision of Long-Acting Reversible Contraception in Community Health Centers [PDF]

open access: yes, 2019
Objective To compare the proportion of women receiving same-day long-acting reversible contraception (LARC) between two different models of contraceptive provision adapted from the Contraceptive CHOICE Project. Study Design We used a controlled time-
Buckel, Christina   +4 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Effectiveness of logotheraphy and cognitive-behavioral therapy on life expectancy among students with depression disorder: A clinical traial study

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2021
Background and Objective: In recent years, psychological therapies increasingly used as complementary treatment of group psychotherapy. This study was done to evaluate the effectiveness of logotheraphy and cognitive-behavioral therapy on life expectancy ...
Touba Seghati   +3 more
doaj  

Practice of psychologo-pedagogical help by the resources of reflective#activity approach: case of Denis G.

open access: yesКонсультативная психология и психотерапия, 2015
There is the case of psychologo-pedagogical help to a student with educational problems by the resources of reflective-activity approach. The case shows the importance of position of agency on learning activity not only for the successful overcoming of ...
Zaretsky V.K., Zaretsky Yu.V.
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Clinico-epidemiological profile of orofacial clefts among children of coastal district of Southern India: A 5 year hospital based study

open access: yesJournal of Cleft Lip Palate and Craniofacial Anomalies, 2014
Background: In India with a large multi ethnic population, most of the epidemiological studies on cleft lip/palate (CL/P) have been sporadic. Inequalities exist, both in access to and quality of cleft care with distinct differences in urban versus rural ...
Supriya Nambiar   +3 more
doaj   +1 more source

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