Results 81 to 90 of about 502,912 (316)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Jurnal Ilmiah Bimbingan Konseling UndikshaNew students in Islamic boarding schools often face challenges in the process of adjusting due to environmental changes that include social, academic, and religious dimensions.
Rika Fitria +3 more
doaj +1 more source
Evaluation in the Psychological Help: Psychological Group Counseling Experience from Members' Eyes
, 2023 Psychological counseling groups are distinguished from other groups by their intense therapeutic effect. This study was conducted to address questioning and disclosing members' perceptions of the group counseling process which is considered a gap in the ...
Güneş, Birkan +2 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Large Language Models for Pre-mediation Counseling in Medical Disputes: A Comparative Evaluation against Human Experts [PDF]
Healthcare Informatics ResearchObjectives Assessing medical disputes requires both medical and legal expertise, presenting challenges for patients seeking clarity regarding potential malpractice claims.
Min Seo Kim, Jung Su Lee, Hyuna Bae
doaj +1 more source
Learning journals as a counseling strategy
, 2002 The effects of counseling have been subject to extensive examination including the meta-analyses of Lipsey and Wilson (1993) and Matt and Navarro (1997).
David, Meacham, Burnett, Paul C.
core
Guidance and counseling have ontological, epistemological, and axiological foundations that are the basis for the implementation of services both in schools and outside schools.
Purwanta, Edi +2 more
core +1 more source
Program evaluation on Centennial Middle School's counseling program [PDF]
, 2000 Plan BThe purpose of this study was to describe students' knowledge and perceptions of the counseling services provided by the school counselors at Centennial Middle School.
Geraghty, Shiloh
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source