Results 231 to 240 of about 552,145 (309)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Pharmacists' recognition, support strategies, and perceived challenges in caring for patients with limited medication literacy in Saudi Arabia: A quasi-experimental study. [PDF]

Explor Res Clin Soc Pharm
Alhomoud F.
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The effect of a digital gamified breastfeeding counselling program on breastfeeding self-efficacy, breastfeeding success, and breast-related problems: a randomized controlled trial in Turkiye. [PDF]

Health Educ Res
Bulut OU, Golbasi Z.
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Preferences regarding preconceptional and genetic counselling and pregnancy check-ups among women with the PLN p. (Arg14del) variant. [PDF]

Neth Heart J
Hogenhout SA, Prins JR, van Spaendonck-Zwarts KY, Cox MGPJ, Gordijn SJ, van der Meer P, Abheiden CNH.   +6 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Barriers and Facilitators of Compliance with Iron-Folic Acid Supplementation Among Pregnant Women in Southern Afghanistan: A Qualitative Study. [PDF]

Patient Prefer Adherence
Stanikzai MH, Le CN, Isaramalai SA, Punsaward C, Ezadi Z, Sayam H, Shohaimi S, Dadras O, Suwanbamrung C.   +8 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Tele-mental health for frail older adults in rural Bangladesh: a phenomenological study. [PDF]

BMC Psychol
Manna RM, Rahman MH, Chandra P, Usmani NG, Majid T, Juthi JM, Shahrin F, Shams SA, Afroze F, Islam SMH, Shomik MS, Ahmed A, El Arifeen S, Rahman AE, Hossain AT.   +14 more
europepmc   +1 more source