Results 101 to 110 of about 1,547,687 (315)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Spatial patterns and determinants of fertility levels among women of childbearing age in Nigeria

open access: yesSouth African Family Practice, 2017
Background: Despite aggressive measures to control the population in Nigeria, the population of Nigeria still remains worrisome. Increased birth rates have significantly contributed to Nigeria being referred to as the most populous country in Africa ...
Oluwayemisi O Alaba   +2 more
doaj   +1 more source

count-data-large intestine-annotated.rds

open access: yes, 2021
tissue-specific single-cell read count data showing the changes with ...
Robert Palovics (9552968)
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Data structures for distributed counting

open access: yesJournal of Computer and System Sciences, 1984
A new type of data structures for a redundant representation of integers is presented. Contrary to binary representation, not only the right end, but every second position in the representation is able to accept orders to increase or decrease the integer value by 1.
openaire   +1 more source

A simple bivariate count data regression model [PDF]

open access: yes
This paper develops a simple bivariate count data regression model in which dependence between count variables is introduced by means of stochastically related unobserved heterogeneity components. Unlike existing commonly used bivariate models, we obtain
Shiferaw Gurmu, John Elder
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

ON BASELINE CONDITIONS FOR ZERO-INFLATED LONGITUDINAL COUNT DATA [PDF]

open access: yes
We describe a mixed-effects hurdle model for zero-inflated longitudinal count data, where a baseline variable is included in the model specification. Association between the count data process and the endogenous baseline variable is modeled through a ...
Valentina Raponi, Antonello Maruotti
core  

count-data-fat MAT-annotated.rds

open access: yes, 2021
tissue-specific single-cell read count data showing the changes with ...
Robert Palovics (9552968)
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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