Results 151 to 160 of about 24,139,341 (352)

Prediction of ICU admission for COVID-19 patients: a Machine Learning approach based on Complete Blood Count data

, 2021
Lorenzo Famiglini, Giorgio Bini, Anna Carobene, Andrea Campagner, Federico Cabitza   +4 more
openalex   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Hierarchical Bayesian modeling of multiregion brain cell count data. [PDF]

Elife
Dimmock S, Exley BMS, Moore G, Menage L, Delogu A, Schultz SR, Warburton EC, Houghton CJ, O'Donnell C.   +8 more
europepmc   +2 more sources

SEX, LIES, AND SELF-REPORTED COUNTS: BAYESIAN MIXTURE MODELS FOR LONGITUDINAL HEAPED COUNT DATA VIA BIRTH-DEATH PROCESSES [PDF]

, 2014
Forrest W. Crawford, Robert E. Weiss, Marc A. Suchard, Ucla Fielding, David Geen   +4 more
openalex  

A Hierarchical Framework for Correcting Under-Reporting in Count Data

, 2019
Oliver Stoner, Theo Economou, Gabriela Drummond Marques da Silva   +2 more
openalex   +1 more source

Zero-Truncated Poisson Regression for Sparse Multiway Count Data Corrupted by False Zeros [PDF]

, 2022
Óscar López, Daniel Dunlavy, Richard B. Lehoucq   +2 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

A robust contaminated discrete Weibull regression model for outlier-prone count data [PDF]

Divan A. Burger, Janet van Niekerk, Emmanuel Lesaffre   +2 more
openalex   +1 more source

Deep dynamic co-clustering of streams of count data: a new online Zip-dLBM

, 2023
Giulia Marchello, Marco Corneli, Charles Bouveyron   +2 more
openalex   +1 more source