Results 71 to 80 of about 24,139,341 (352)

iid2022: a workshop on statistical methods for event data in astronomy

Frontiers in Astronomy and Space Sciences, 2023
We review the iid2022 workshop on statistical methods for X-ray and γ-ray astronomy and high–energy astrophysics event data in astronomy, held in Guntersville, AL, on Nov. 15–18 2022.
Eric D. Feigelson, Massimiliano Bonamente   +1 more
doaj   +1 more source

Negative binomial mixed models for analyzing microbiome count data

BMC Bioinformatics, 2017
Recent advances in next-generation sequencing (NGS) technology enable researchers to collect a large volume of metagenomic sequencing data. These data provide valuable resources for investigating interactions between the microbiome and host environmental/
Xinyan Zhang, Himel Mallick, Zaixiang Tang, Lei Zhang, X. Cui, A. Benson, N. Yi   +6 more
semanticscholar   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Policy Changes and the Demand for Lottery-Rationed Big Game Hunting Licenses

Journal of Agricultural and Resource Economics, 2000
Lotteries are commonly used to allocate big game hunting privileges. In this study, lottery demand and consumer surplus are modeled before and after policy changes designed to increase participation.
David Scrogin, Robert P. Berrens, Alok K. Bohara   +2 more
doaj   +1 more source

DEBrowser: interactive differential expression analysis and visualization tool for count data

BMC Genomics, 2018
Sequencing data has become a standard measure of diverse cellular activities. For example, gene expression is accurately measured by RNA sequencing (RNA-Seq) libraries, protein-DNA interactions are captured by chromatin immunoprecipitation sequencing ...
Alper Kucukural, O. Yukselen, Deniz M. Ozata, M. Moore, Manuel Garber   +4 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Naught all zeros in sequence count data are the same

bioRxiv, 2018
Due to the advent and utility of high-throughput sequencing, modern biomedical research abounds with multivariate count data. Yet such sequence count data is often extremely sparse; that is, much of the data is zero values.
J. Silverman, K. Roche, Sayan Mukherjee, Lawrence A. David   +3 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

GMPR: A robust normalization method for zero-inflated count data with application to microbiome sequencing data

PeerJ, 2018
Normalization is the first critical step in microbiome sequencing data analysis used to account for variable library sizes. Current RNA-Seq based normalization methods that have been adapted for microbiome data fail to consider the unique characteristics
Li Chen, J. Reeve, Lu Zhang, Shengbing Huang, Xuefeng Wang, Jun Chen   +5 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source