Closed-Loop Recycling Dual-Mode Counter-Current Chromatography with Specified Sample Loading Durations: Modeling of Preparative and Industrial-Scale Separations [PDF]
Molecules, 2021 We previously reported on a new counter-current chromatography (CCC) operating mode called closed-loop recycling dual-mode counter-current chromatography (CLR DM CCC), which incorporates the advantages of closed-loop recycling (CLR) and dual-mode (DM ...
Artak E. Kostanyan, Andrey A. Voshkin
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Continuous Affinity Purification of Adeno-Associated Virus Using Periodic Counter-Current Chromatography [PDF]
Pharmaceutics, 2022 Replacing batch unit operations of biopharmaceuticals by continuous manufacturing is a maturing concept, with periodic counter-current chromatography (PCC) favoured to replace batch chromatography.
João P. Mendes +5 more
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Two-phase Motion in Hydrodynamic Counter-current Chromatography. [PDF]
Curr Chromatogr, 2020 Background: Motion of the two mutually immiscible liquids in hydrodynamic countercurrent chromatographic systems is speculated based on the observation of their behavior in a closed coiled tube rotating in unit gravity. Materials and Methods: The experiment revealed an up and down pattern of four stages of twophase volume ratio occupied at the head ...
Ito Y.
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Counter-current motion in counter-current chromatography. [PDF]
J Chromatogr A, 2014 After the CCC2012 meeting, I have received an e-mail regarding the terminology of "Countercurrent Chromatography". It stated that the term "Countercurrent" is a misnomer, because its stationary phase is motionless in the column and that the method should be renamed as liquid-liquid separations or centrifugal separations.
Ito Y.
europepmc +4 more sources
Preparative Fractionation of Brazilian Red Propolis Extract Using Step-Gradient Counter-Current Chromatography [PDF]
MoleculesPropolis is a resinous bee product with a very complex composition, which is dependent upon the plant sources that bees visit. Due to the promising antimicrobial activities of red Brazilian propolis, it is paramount to identify the compounds responsible ...
Begoña Gimenez-Cassina Lopez +7 more
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A Novel 3D-Printed and Miniaturized Periodic Counter Current Chromatography System for Continuous Purification of Monoclonal Antibodies [PDF]
MicromachinesContinuous chromatography has emerged as one of the most attractive methods for protein purification. Establishing such systems involves installing several chromatographic units in series to enable continuous separation processes and reduce the cost of ...
Carlotta Kortmann +4 more
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A multilayer coil in type-I counter-current chromatography. [PDF]
J Chromatogr A, 2018 In the present study, a novel model of type-I counter-current chromatography was developed to simplify the separation column manufacture and extend its application ranges. In this system, a multilayer coil was used as the separation column of type-I counter-current chromatography for the first time. The chromatographic performance of this apparatus was
Yang Y +5 more
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Identifying Natural syNergist from Pongamia pinnata Using High-Speed Counter-Current Chromatography Combined with Isobolographic Analysis [PDF]
Molecules, 2017 For identifying the synergistic compounds from Pongamia pinnata, an approach based on high-speed counter-current chromatography (HSCCC) combined with isobolographic analysis was designed to detect the synergistic effects in the complex mixture [...]
Hao Yin +7 more
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One-Step Preparative Separation of Flavone and Isoflavone Glycosides from Sophora Japonica Fruit by High-Speed Counter-Current Chromatography Based on COSMO-RS Model [PDF]
International Journal of Nutrition Sciences, 2021 Background: Sophora japonica L. (Leguminosae), a well-known traditional medicine in Asia, is offcially listed in the Chinese and European Pharmacopoeia.
Zhao Wang, Yang Liu, Chen Fan, Xueli Cao
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Vortex counter-current chromatography [PDF]
Journal of Chromatography A, 2011 A novel counter-current chromatographic system is developed by mounting a vortex column on a type-I coil planet centrifuge. The column is fabricated from a high-density polyethylene disk (16 cm diameter and 5 cm thick) by making multiple holes of various diameters (3-12.5 mm) each arranged in a circle and connected with narrow transfer ducts.
Yoichiro, Ito +5 more
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