Results 31 to 40 of about 11,225 (310)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Radical Americas, 2021 The election of Salvador Allende and the Unidad Popular (Popular Unity) in 1970 unleashed a radical and original revolutionary process, discernible not only in the depth of its redistributive measures and the expectations it generated, but also in the ...
doaj +2 more sources
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Post-hegemonic destructive counter-translation [PDF]
Filozofija i DruštvoWe have been through a destructive post-hegemonic reactionary revolution. We witnessed post-hegemonic globalisation (not global) and post-socialist new wars, nearest to (post-)colonial wars.
Iveković Rada
doaj +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Nuevo mundo - Mundos Nuevos, 2016 This article aims to analyze the relations in between the French and Brazilian military officers. Its purposes are to understand the importance of anticommunism in the bilateral dialogue.
Rodrigo Nabuco de Araujo
doaj +1 more source
FEBS Open Bio, EarlyView.A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li +7 more
wiley +1 more source
Romanian Revolution, after 20 years. The vices and virtues of social normality
Sfera Politicii, 2013 In this study the author investigates the "dilemmas" of the Romanian Revolution. He is inquiring into the events taking place during the first half of the 90's, along with Romania's geopolitical evolution.
Adrian Cioroianu
doaj
Counter-revolutionary transformations of Charles I in Burke, Austen and Scott
Journal of English Studies, 2016 Few would deny Charles I’s uniqueness in British history. The voluminous interpretations of Charles since his execution amply indicate the impact of his myth on subsequent generations. This essay considers mythologizings of the executed monarch by Edmund
Dani Napton, A. D. Cousins
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Ethical Foreground and Background in Adult Educator Work
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley +1 more source