Results 131 to 140 of about 9,057 (255)

The Emergence of Novel Benzodiazepines in Australia, Evidence, Alerts, Clinical Management and Harm Reduction-A Narrative Review. [PDF]

open access: yesDrug Alcohol Rev
Freestone J   +13 more
europepmc   +1 more source

Unified Synthesis of Unconventional α‐Polyhalogenated Amines Through Hydroaminoalkylation

open access: yesAngewandte Chemie International Edition, EarlyView.
A unified, redox‐neutral method that transforms alkenes and alkynes into α‐polyhalomethyl amines using stable hemiaminal reagents is reported. This approach enables access to CF3, CF2H, CF2Cl, and CFClH motifs, expanding halogenated amine space with broad substrate scope, functional group tolerance, and applicability to late‐stage modification of drug ...
Angela K. Hofmeister   +9 more
wiley   +1 more source

Highly Enantio‐ and Diastereoselective Synthesis of Tetrahydrofuran Frameworks via Chiral Lewis Acid‐Catalyzed Formal [3+2] Cycloaddition of Allylsilanes

open access: yesAngewandte Chemie International Edition, EarlyView.
The first catalytic asymmetric formal [3+2] cycloaddition of allylsilanes delivers cis‐2,5‐disubstituted tetrahydrofuran‐3‐ones that serve as versatile intermediates for the synthesis of diverse bioactive scaffolds. ABSTRACT A formal [3+2] cycloaddition via cyclization/1,2‐hydride shift initiated by nucleophilic attack of allylsilanes has been ...
Hosung Lee   +5 more
wiley   +1 more source

Redefining Counterfeit Medicines and Updating the Legal Framework to Address Falsified Medicines: A Qualitative Policy Review. [PDF]

open access: yesActa Med Philipp
Peña IG   +6 more
europepmc   +1 more source

The hidden peril: Ecuador's struggle with substandard and falsified medicines. [PDF]

open access: yesFront Public Health
Vasconez-Gonzalez J   +2 more
europepmc   +1 more source

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