Results 201 to 210 of about 34,472 (250)

Market size and strategic interaction in pharmaceutical price regulation

open access: yesThe Scandinavian Journal of Economics, EarlyView.
Abstract We present a model of optimal regulation in the presence of spillover effects and asymmetric countries, and we use it to study strategic interaction among countries in pharmaceutical price regulation, where the spillovers result from innovation in drug development.
Simona Gambaⓡ   +2 more
wiley   +1 more source

Partially countering the physiological effects of fentanyl with naloxone or d-cysteine ethyl ester in adult goats. [PDF]

open access: yesJ Appl Physiol (1985)
Taylor R   +8 more
europepmc   +1 more source

Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression

open access: yesExperimental Physiology, EarlyView.
Abstract The effects of muscle disuse on the propagation of action potentials along motor unit (MU) muscle fibres, a key process for effective muscle activation and force generation, remain poorly understood. The aim of this study was to investigate changes in action potential propagation and to identify biological factors influencing these changes ...
Giacomo Valli   +12 more
wiley   +1 more source

Cerebrovascular regulation during heat stress

open access: yesExperimental Physiology, EarlyView.
Abstract Given that the brain is a highly metabolic organ and is enclosed by the skull, effective regulation of cerebral blood flow (CBF), not only for oxygen and nutrients supply but also as a means of convective heat exchange, is critical for preventing excessive elevations in brain temperature.
Kanoko Ito, Manabu Shibasaki
wiley   +1 more source

Limited musculoskeletal benefits of artificial gravity combined with cycling during bed rest: Results from the BRACE study. [PDF]

open access: yesExp Physiol
Mandić M   +7 more
europepmc   +1 more source

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

open access: yesExperimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin   +8 more
wiley   +1 more source

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