Results 161 to 170 of about 117,551 (283)

SWEET tea: transcriptional regulation of sugar transporters in stress and development. [PDF]

J Exp Bot
Zhang X, Liesche J.
europepmc   +1 more source

Hypercube matrix computation task [PDF]

The Hypercube Matrix Computation (Year 1986-1987) task investigated the applicability of a parallel computing architecture to the solution of large scale electromagnetic scattering problems. Two existing electromagnetic scattering codes were selected for
Calalo, R., Imbriale, W., Liewer, P., Lyons, J., Manshadi, F., Patterson, J.   +5 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

COUNTERPOINT: Should the Progressive Pulmonary Fibrosis Clinical Practice Guideline Be Adopted for Clinical Practice? No. [PDF]

Chest
Oldham JM, Cottin V.
europepmc   +1 more source

A counterpoint reading of the MoussemCities@Tunis festival [PDF]

, 2016
Ben Yakoub, Joachim, Hammami, Fida
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Point-Counterpoint: Cascade reporting-useful tool to support antimicrobial stewardship, or dangerously misleading. [PDF]

J Clin Microbiol
Kuti JL, Lutgring JD, Simner PJ, Naccache SN, Heil EL.   +4 more
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Stefan Prey, Algorithmen zur Satztechnik und ihre Anwendung auf die Analyse, Phil. Diss., Universität Osnabrück 2012 Immanuel Ott, Methoden der Kanonkomposition bei Josquin Des Prez und seinen Zeitgenossen (= Schriften der Musikhochschule Lübeck, Bd. 1), Hildesheim: Olms 2014 [PDF]

Zeitschrift der Gesellschaft für Musiktheorie, 2017
Michael Polth
doaj   +1 more source

Remyelination therapies are achievable in clinical practice-Yes. [PDF]

Mult Scler
Zuroff L, Cordano C, Green AJ.
europepmc   +1 more source