Results 251 to 260 of about 856,429 (315)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Key Considerations for Photon-Counting CT versus Energy-Integrating Detector CT in the Evaluation of Lung Cancer. [PDF]

J Korean Soc Radiol
Jin GY.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A Movement Description Language for Functional Training Exercise Analysis. [PDF]

J Funct Morphol Kinesiol
Sousa L, Canedo D, Santos P, Neves A.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Fourier transform-based single domain generalization for crowd counting. [PDF]

Sci Rep
Song L, Li T, Cai Z, Guo J, He J, Xie J, Zhang Y.   +6 more
europepmc   +1 more source

Classification of outcomes in antimalarial therapeutic efficacy studies with Aster. [PDF]

Antimicrob Agents Chemother
Gerlovina I, Berube S, Briggs J, Murie K, Murphy M, Wesolowski A, Greenhouse B.   +6 more
europepmc   +1 more source

Oblique-view video tracking and density-based counting: accurate counting of late-stage rapeseed seedlings for breeding assessment. [PDF]

Front Plant Sci
Luo B, Yang Y, Zhang K, Lv X, Liu Y, Yang Y, Zhang F, Liu L, Zhang G, Wang X, Wu Z.   +10 more
europepmc   +1 more source