Results 201 to 210 of about 175,606 (309)

DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout

open access: yesAdvanced Science, EarlyView.
A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li   +12 more
wiley   +1 more source

Precision Lignocellulosic Biorefinery: Process Regulation From Corn Stover to Products

open access: yesAdvanced Science, EarlyView.
This study presents a precision biorefinery framework that transforms corn stover into high‐value bioproducts through whole‐process regulation. Mechanical fractionation separates feedstock into parenchyma‐rich short fibers and vascular‐bundle‐dominant long fibers.
Xue‐Cheng Lin   +4 more
wiley   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

open access: yesAdvanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole   +17 more
wiley   +1 more source

Bionic Solar‐Powered Heavy Metal Trap for Eco‐Friendly Sludge Drying and Simultaneous Electricity Generation

open access: yesAdvanced Science, EarlyView.
Herein, we propose a solar‐powered heavy metal trap (SPHT) for sludge disposal. The indoor experiments demonstrated that the sludge water content decreased from 90 % to 31 %, coupled with a decrease in heavy metal content to 6 % at most. Furthermore, the designed SPHT generated an initial potential of 0.10 V, and monitoring this hydrovoltaic potential ...
Yanlin Li   +7 more
wiley   +1 more source

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

open access: yesAdvanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin   +12 more
wiley   +1 more source

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