Results 91 to 100 of about 616,847 (259)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Relationship education and counselling: recent research findings [PDF]
, 2015 This paper reviews the research on relationship education and relationship counselling. The paper investigates the effectiveness of these strategies in working with couples who are at varying stages of their relationship - from highly satisfied at the ...
Cathryn Hunter, Joanne Commerford
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
, 2009 The aim of the current study was to test predictors of sustained relationship satisfaction after couple relationship education (CRE). Sixty-six couples, who were stratified into high- and low-risk for future relationship problems groups, completed the ...
Kim Halford, W. +3 more
core +1 more source
Union Minister felicitates fisher couple The Hindu dated 6th May 2017 [PDF]
, 2017 It was a memorable wedding anniversary gift for K.V. Karthikeyan and K.C. Rekha, said to be India’s first fisher couple, when they were felicitated by Minister of State for Agriculture and Farmer’s Welfare Sudarshan Bhagat at a function organised by the ...
CMFRI, Library
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Le couple à l'heure de la retraite
, 1996 Quand sonne l'heure de la retraite, quand disparaissent les contraintes de l'activité professionnelle, le nouveau retraité se retrouve face à lui-même… et face à son conjoint. C'est une nouvelle étape de la vie conjugale qui commence alors.
Vincent Caradec
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Le sort du logement familial loué ou en propriété lors d'une rupture d'un couple non marié
, 2016 Le sort du logement familial loué ou en propriété lors d'une rupture d'un couple non ...
Demortier, Alexandra +2 more
core
HIV and dyadic intervention: an interdependence and communal coping analysis. [PDF]
, 2012 BACKGROUND: The most common form of HIV transmission in sub-Saharan Africa is heterosexual sex between two partners. While most HIV prevention interventions are aimed at the individual, there is mounting evidence of the feasibility, acceptability, and ...
Montgomery, Catherine M +8 more
core +2 more sources