Results 61 to 70 of about 616,847 (259)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The efficacy of positive couple therapy and treatment based on acceptance and commitment on the desire for divorce

open access: yesمجله علوم روانشناختی, 2021
Background: Research has shown that positivist psychotherapy leads to marital adjustment and a reduction in the desire for divorce in couples. On the other hand, acceptance and commitment therapy has been effective in reducing issues such as conflict and
Bomyad Jamshidzehi   +2 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

[News Clip: Air Force Couple Rescued]

open access: yes, 1960
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about a couple who were found unconscious in their home in ...
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An approach based on distributed dislocations and disclinations for crack problems in couple-stress elasticity [PDF]

open access: yes, 2008
The technique of distributed dislocations proved to be in the past an effective approach in studying crack problems within classical elasticity. The present work is intended to extend this technique in studying crack problems within couple-stress ...
Gourgiotis, P.A.   +5 more
core   +1 more source

A fisher couple who defies conventions The Hindu dated 4th May 2017 [PDF]

open access: yes, 2017
The Central Marine Fisheries Research Institute (CMFRI) will felicitate K.V. Karthikeyan and his wife K.C. Rekha who have been venturing into the sea for fishing using gill nets and hooks since the past 13 years.
CMFRI, Library
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Family’s functioning and adaptationin married couples with violation of family health and different women’s addictive status

open access: yesJournal of Education, Health and Sport, 2016
Savina M. V. Family’s functioning and adaptationin married couples with violation of family health and different women’s addictive status. Journal of Education, Health and Sport. 2016;6(9):1004-1014. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.
M. V. Savina
doaj  

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