Results 61 to 70 of about 524,795 (317)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Lasting couple relationships: recent research findings [PDF]
This paper reviews recent research findings into couples in long-term relationships (married and de facto) that provide insight into the couple relationship over time.
Robyn Parker, Joanne Commerford
core
Introduction: Parenthood is a composite experience in which personal, couple, relational, environmental, historical and cultural variables interact. In recent years, western societies have experienced a steady downward trend in the birth rate.
Paola Manfredi, Cesare Tomasi
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Role of Islamic Beliefs in Facilitating Acceptance of Cancer Diagnosis
Although survival rates for patients with cancer have increased, this disease continues to affect couples significantly. Religion and culture seem to be part of the therapeutic process for people with cancer.
Amina Benidir +2 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Web-Based Couple Interventions: Do They Have a Future? [PDF]
To examine the current and potential future impact of formal and informal resources to enhance romantic relationships, 1,160 individuals were surveyed. When asked about resources previously used, participants reported that numerous forms of relationship ...
Georgia, Emily J, Doss, Brian D
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
This article analyzes the deployment of misogynistic stereotypes in a corpus consisting of text messages and emails sent by male ex-spouses to a female co-parent recipient.
Aude Laferrière
doaj +1 more source
Genetics of recurrent miscarriage: challenges, current knowledge, future directions.
Recurrent miscarriage (RM) occurs in 1-3% of couples aiming at childbirth. Due to multifactorial etiology the clinical diagnosis of RM varies. The design of genetic/’omics’ studies to identify genes and biological mechanisms involved in pathogenesis of ...
Kristiina eRull +3 more
doaj +1 more source

