Results 111 to 120 of about 226,952 (278)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Open Engineering, 2016 This study is an investigation of fully-developed laminar flow in a two-layer vertical channel; one part filled with couple stress nanofluid and the other part with clear couple stress fluid. The flow is examined for combined heat and mass transfer using
Khan Najeeb Alam +3 more
doaj +1 more source
Pore-scale modeling of fluid-particles interaction and emerging poromechanical effects
, 2013 A micro-hydromechanical model for granular materials is presented. It combines the discrete element method (DEM) for the modeling of the solid phase and a pore-scale finite volume (PFV) formulation for the flow of an incompressible pore fluid.
Barthélémy, Eric +2 more
core +2 more sources
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
, 2009 We have conducted a triple-scale simulation of liquid water by concurrently coupling atomistic, mesoscopic, and continuum models of the liquid. The presented triple-scale hydrodynamic solver for molecular liquids enables the insertion of large molecules ...
Delgado-Buscalioni, Rafael +2 more
core +1 more source
A Class of Flows for Couple Stress Fluids
Journal of Basic & Applied Sciences, 2012 Exact solutions are derived for a class of two dimensional couple stress flows. This class consists of flows for which the vorticity distribution is characterized by the Eq. (12). The solutions are obtained by introducing the functions Ψ, H and the canonical transformation.
openaire +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Effect of Couple-Stress on Peristaltic Transport of Sutterby Fluid in an Asymmetric Channel
Ibn Al-Haitham Journal for Pure and Applied SciencesIn this paper, the effect of a couple–stress and other variables on the peristaltic flow of Sutterby fluid in an inclined asymmetric channel containing a porous medium with heat transfer is examined.
Asmaa Mohammed, Liqaa Zeki Hummady
doaj +1 more source
Squeeze Film Lubrication between Porous Parallel Stepped Plates with Couple Stress Fluids
Tribology Online, 2013 This paper presents the theoretical study of squeeze film lubrication between porous parallel stepped plates with couple stress fluids. The lubricant with additives in the film region and also in the porous region in modeled as Stokes couple stress fluid.
Trimbak Vaijanath Biradar
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source