Results 181 to 190 of about 380,039 (299)

Inside Alcohol Behavioral Couple Therapy (ABCT): In-session speech trajectories and drinking outcomes. [PDF]

J Subst Abuse Treat, 2020
Fokas KF, Houck JM, McCrady BS.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Effects of integrative behavioral couple therapy on communication patterns and marital adjustment. [PDF]

J Educ Health Promot
Salimi C, Kachooei M, Dadashi M, Farahani H.   +3 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

An Initial Examination of Couple Therapy for PTSD Outcomes Among Black/African American Adults: Findings from an Uncontrolled Trial with Military Dyads. [PDF]

Behav Sci (Basel)
Fredman SJ, Gamaldo AA, Jenkins AIC, Le Y, Mogle JA, Monson CM, Gamaldo CE, Thorpe RJ, Hall-Clark BN, Blount TH, Fina BA, Buxton OM, Engeland CG, Rhoades GK, Stanley SM, Macdonald A, Dondanville KA, Taylor DJ, Pruiksma KE, Litz BT, Young-McCaughan S, Yarvis JS, Keane TM, Peterson AL, Consortium to Alleviate PTSD.   +24 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Emotion Regulation Difficulties as a Mediator Between Relationship Satisfaction Predicting Depressive Symptom Trajectories Among Couples in Couple Therapy. [PDF]

Behav Sci (Basel)
Morgan PC, Wittenborn AK, Morlan GL, Snyder R.   +3 more
europepmc   +1 more source

New Model for Couple Therapy for Patients with Chronic Pain and their Caregivers: An Attempt to Improve Quality of Life and Reduce Pain. [PDF]

Clin Pract Epidemiol Ment Health, 2020
Rouhi S, Dadkhah P, Firoozi M, Hashemi M.   +3 more
europepmc   +1 more source

Rituals, Images and Stories: A Narrative Conversation [PDF]

, 1999
Marcon, Evelyn M.
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source