Results 181 to 190 of about 2,413,185 (355)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

A new single magnetic core coupled-inductor based active switched Quasi Z-source inverter. [PDF]

Sci Rep
Zarrinehbafan M, Seifi A, Nadermohammadi A, Hosseini SH.   +3 more
europepmc   +1 more source

A Family of Four Quadrant DC/DC Converters with Reduced Number of Components [PDF]

, 2015
Mostaan, Ali, Soltani, Mohsen
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Topology synthesis of coupled inductor based four port DC-DC converter for multi-input PV-battery application with autonomous mode selection. [PDF]

Sci Rep
S SK, S P, Ms K.
europepmc   +1 more source

Magnetic Integration for Parallel Interleaved VSCs Connected in a Whiffletree Configuration [PDF]

, 2016
Bede, Lorand, Blaabjerg, Frede, Gohil, Ghanshyamsinh Vijaysinh, Kerekes, Tamas, Teodorescu, Remus   +4 more
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Design of a high voltage gain converter using coupled inductor with reduced voltage stress for photovoltaic energy based systems. [PDF]

Sci Rep
Hashemzadeh SM, Hosseini SH.
europepmc   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

New structure of step-up DC-DC converter based on three winding coupled inductor with high gain capability featuring integrated renewable energy applications. [PDF]

Sci Rep
Aghakhanlou P, Falahi F, Nadermohammadi A, Sarikhan H, Hosseini SH, Rostami N, Sabahi M.   +6 more
europepmc   +1 more source