Results 151 to 160 of about 1,462,493 (311)

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Coupled fixed point theorems in G b -metric space satisfying some rational contractive conditions. [PDF]

Springerplus, 2016
Khomdram B, Rohen Y, Singh TC.
europepmc   +1 more source

Coupled fixed point theorems in partially ordered cone metric spaces

, 2011
Hui-Sheng Ding, Lu Li
openalex   +2 more sources

Coupled fixed point theorems for contractions involving altering distances in ordered metric spaces [PDF]

, 2013
Hemant Kumar Nashine, Hassen Aydi
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Common coupled fixed point theorems satisfying rational type contractive conditions in b-metric spaces. [PDF]

Springerplus, 2016
Sarwar M, Hussain S, Kumari PS.
europepmc   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Fixed and coupled fixed point theorems of omega-distance for nonlinear contraction [PDF]

, 2013
Wasfı Shatanawi, Ariana Pitea
openalex   +1 more source

Common Coupled Fixed Point Theorems for Two Hybrid Pairs of Mappings under φ-ψ Contraction. [PDF]

Int Sch Res Notices, 2014
Deshpande B, Handa A.
europepmc   +1 more source

Some coupled coincidence and common fixed point results for a hybrid pair of mappings in 0-complete partial metric spaces [PDF]

, 2013
Wei Long, Satish Shukla, Stojan Radenović, S. Radojević   +3 more
openalex   +1 more source