Results 151 to 160 of about 2,303,991 (326)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Coupled Fixed Points of monotone mappings in a metric space with a graph [PDF]

open access: yesarXiv, 2018
In this work, we define the concept of mixed $G$-monotone mappings defined on a metric space endowed with a graph. Then we obtain sufficient conditions for the existence of coupled fixed points for such mappings when a weak contractivity type condition is satisfied.
arxiv  

On coupled fixed point theorems on partially ordered G-metric spaces [PDF]

open access: gold, 2012
Erdal Karapınar   +2 more
openalex   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Mixed monotone-generalized contractions in partially ordered probabilistic metric spaces

open access: yesFixed Point Theory and Applications, 2011
In this article, a new concept of mixed monotone-generalized contraction in partially ordered probabilistic metric spaces is introduced, and some coupled coincidence and coupled fixed point theorems are proved.
Agarwal Ravi   +2 more
doaj  

Coupled common fixed point theorems for mixed weakly monotone mappings in partially ordered metric spaces [PDF]

open access: gold, 2012
M‎. ‎Eshaghi Gordji   +3 more
openalex   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Common Coupled Fixed Point Theorems of Single-Valued Mapping for c-Distance in Cone Metric Spaces

open access: yesAbstract and Applied Analysis, 2012
The existence and uniqueness of the common coupled fixed point in cone metric spaces have been studied by considering different types of contractive conditions.
Zaid Mohammed Fadail   +1 more
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

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