Results 41 to 50 of about 124,050 (314)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Dynamic energy flow analysis of electricity-heating based integrated energy system
Energy Reports, 2023 With the development of integrated energy system, energy flow analysis of coupling energy network has attracted much attention. In this study, based on the unified energy path theory, energy flow analysis of electricity-heating coupled energy system is ...
Qiong Wu +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Experimental research on heat transfer in a coupled heat exchanger
Thermal Science, 2013 The heat exchanger is a devise used for transferring thermal energy between two or more different temperatures. The widespreadly used heat exchanger can only achieve heat exchange between two substances. In this paper, a coupled heat exchanger is proposed, which includes a finned heat exchanger and a double pipe heat exchanger, for multiple
Yin Liu +3 more
openaire +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Analysis of Fluid Flow and Heat Transfer Characteristics for Radial Ventilation Generator
Journal of Harbin University of Science and Technology, 2019 In order to study distribution of fluid flow, the characteristic of heat transfer,and temperature rise characteristics of radial ventilation generator，a mathematical and physical model of 3D fluid flow and heat transfer coupled was established according ...
DING Shu-ye +4 more
doaj +1 more source
A fractional model of magnetohydrodynamics Oldroyd-B fluid with couple stresses, heat and mass transfer: A comparison among Non-Newtonian fluid models [PDF]
, 2023 Muhammad Arif +3 more
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Simulation Analysis and Experiment Study of the Fluid- solid Coupled Heat Transfer of Disc Brake
Jixie chuandong, 2016 The fluid-solid coupled heat transfer analysis focus on computational fluid dynamics（ CFD）and solid heat transfer finite elements（ FEA）. The partition solving and boundary coupling are used to study a fluid-solid coupled heat transfer system which is ...
Zeng Hong +3 more
doaj