Results 51 to 60 of about 124,050 (314)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Gas-Solid Heat Transfer Computation from Particle-Resolved Direct Numerical Simulations
Fluids, 2021 Particle-Resolved simulations (PR-DNS) have been conducted using a second order implicit Viscous Penalty Method (VPM) to study the heat transfer between a set of particles and an incompressible carrier fluid.
Mohamed-Amine Chadil +2 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Chemical Engineering Transactions, 2023 The Renewable Energy System for Residential Building Heating and Electricity Production (RESHeat ) system is a typical application of the utilisation of sun-tracked Photovoltaic Thermal (PVT) panels and underground heat storage units.
Sheng Zhang +5 more
doaj
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Kongqi donglixue xuebaoRegenerative cooling serves as a vital thermal protection approach for high-speed flight propulsion systems. Quantitatively revealing the fluid-solid coupled heat transfer rules in cooling micro-channels is crucial for the design and optimization of ...
Zhenhua Ren +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
AIP Advances, 2017 Coated silicon carbide (SiC) thin films can efficiently enhance near-field radiative heat transfer among metamaterials. In this study, the near-field heat transfer among graphene–SiC–metamaterial (GSM) multilayer structures was theoretically investigated.
Ting Zhou +7 more
doaj +1 more source