Results 71 to 80 of about 1,148,154 (395)

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

open access: yesFEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling   +4 more
wiley   +1 more source

A Robust Finite Element Modeling Approach to Conjugate Heat Transfer in Flexible Elastic Tubes and Tube Networks [PDF]

open access: yes, 2014
In this work, heat transfer between fluid flow in elastic tubes and external environment is modeled using a robust finite element approach. The transport of energy is coupled to fluid flow that is linked to the pressure and cross-sectional area ...
Alberto Coccarelli, Perumal Nithiarasu
core   +1 more source

Heat Transfer between Weakly Coupled Systems

open access: yes, 2010
13 pages, 8 ...
Persson, B. N. J.   +2 more
openaire   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Enhancement of near-field radiative heat transfer via multiple coupling of surface waves with graphene plasmon

open access: yesAIP Advances, 2017
Coated silicon carbide (SiC) thin films can efficiently enhance near-field radiative heat transfer among metamaterials. In this study, the near-field heat transfer among graphene–SiC–metamaterial (GSM) multilayer structures was theoretically investigated.
Ting Zhou   +7 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Dynamic near-field heat transfer between macroscopic bodies for nanometric gaps

open access: yesNanophotonics, 2018
The dynamic heat transfer between two half-spaces separated by a vacuum gap due to the coupling of their surface modes is modeled using the theory that describes the dynamic energy transfer between two coupled harmonic oscillators, each separately ...
Sasihithlu Karthik, Agarwal Girish S.
doaj   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

A fully coupled seepage–heat transfer model including a dynamic heat transfer coefficient in fractured rock sample with a single fissure

open access: yesGeomatics, Natural Hazards & Risk, 2021
Conventional seepage–heat transfer models in simulating the heat transfer between fluid and rock in fractures mainly involve one-way coupling and do not consider the influence of temperature on the seepage. Moreover, it is an enormous challenge to define
Ze Zhang   +4 more
doaj   +1 more source

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