Results 41 to 50 of about 4,076 (264)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A Coupled Inductor Based High Voltage Gain DC-DC Converter Using Interleaved Voltage Multiplier Cells

open access: yesIranian Journal of Electrical and Electronic Engineering, 2020
In this work, a non-isolated high step up DC-DC converter using coupled inductor and voltage multiplier cell is proposed. The proposed converter conversion ratio is efficiently extended by using a coupled inductor.
S. Pourjafar   +4 more
doaj  

High Step-up Coupled Inductor Inverters Based on qSBIs

open access: yesEnergies, 2019
In this paper, two types of high step-up coupled inductor inverters based on qSBIs (quasi- switched boost inverters) are proposed. By applying the coupled inductor to the qSBIs, the voltage gain of the proposed inverter is regulated by turn ratio and ...
Hongchen Liu, Xi Su, Junxiong Wang
doaj   +1 more source

Unifying Models for Multiphase Coupled Inductors [PDF]

open access: yes, 2020
<div>This paper presents a unified model for multiphase</div><div>coupled inductors. By summarizing and comparing three</div><div>different ways of modeling multiphase coupled inductors, including a) an inductance matrix model derived based on self and mutual inductances; b) a multiwinding transformer model derived based ...
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

open access: yes
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari   +9 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Interleaved ZVS DC‐DC converter with ultrahigh step‐down and flexible gain

open access: yesIET Power Electronics
This paper proposes a novel non‐isolated ultrahigh step‐down interleaved DC‐DC converter with an extremely extended duty cycle based on the series capacitor and coupled‐inductor techniques. The proposed converter utilizes a three‐winding coupled inductor
Wahid Eskandary   +3 more
doaj   +1 more source

Design and analysis of an inductor-less cross-coupled voltage equalizer

open access: yesEnergy Reports, 2020
To equalize the imbalance in the state-of-charge (SoC) of lithium-ion cells, we propose a novel inductor-less cross-coupled voltage equalizer for series-connected batteries.
Kei Eguchi   +3 more
doaj   +1 more source

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