Results 131 to 140 of about 2,903,325 (300)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A microstrip bandpass filter using coupled lines loaded by open stubs
Scientific ReportsA compact simple structure bandpass filter based on terminated three coupled line structures with high selectivity is introduced through odd and even-mode analysis.
Sadegh Heydari Kahkesh, Akram Sheikhi
doaj +1 more source
A New Class of Wideband Quadrature Coupled-Line Forward Couplers
IEEE Journal of MicrowavesThis paper presents a new class of wideband quadrature coupled-line forward couplers making use of the unequal phase velocities of even- and odd-mode of coupled-lines in inhomogeneous media.
Henning Mextorf, Winfried Schernus
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Novel Wideband Microstrip Absorptive Bandstop Filter Utilizing Coupled-Line Architecture
IEEE AccessReflectionless and high-attenuation characteristics are crucial for protecting sensitive front-end components, such as power amplifiers and mixers, in modern communication systems.
Chuan-Jing Jiang, Ching-Wen Tang
doaj +1 more source
Spectrum-line reversal measurements of free electron and coupled N2 vibrational temperature in expansion flows [PDF]
Spectrum line reversal measurements of free electron and coupled nitrogen vibrational temperatures in expansion flow of shock ...
Hurle, I. R., Russo, A. L.
core +1 more source