The free fatty acid 2 receptor regulates C5a induced neutrophil superoxide production and its sensitivity to inhibition by the antagonist avacopan. [PDF]
Khan Z +6 more
europepmc +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Compact Microstrip Fixed-Frequency Double-Coupled Double-Tuned Filter with Selected Band Suppression. [PDF]
Wójcik D, Surma M, Magnuski M.
europepmc +1 more source
Emerging strategies to target metastasis and therapy resistance in melanoma
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley +1 more source
Bipartite entanglement in a nuclear spin register mediated by a quasi-free electron spin. [PDF]
Klotz M +3 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Engineered fano resonances in a compact Si<sub>3</sub>N<sub>4</sub> photonic crystal nanobeam-microring platform for multi-cladding environments. [PDF]
Mendoza-Castro JH +6 more
europepmc +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Lasing-like dynamics with virtual gain driven by complex-frequency excitations. [PDF]
Xue B +6 more
europepmc +1 more source

