Results 121 to 130 of about 1,058,541 (299)

Ecosystems as climate controllers – biotic feedbacks (a review) [PDF]

open access: yes, 2008
There is good evidence that higher global temperature will promote a rise of green house gas levels, implying a positive feedback which will increase the effect of the anthropogenic emissions on global temperatures.
Drégelyi-Kiss, G.   +2 more
core  

Physics of the rhythmic applause

open access: yes, 2000
We discuss in detail a human scale example of the synchronization phenomenon, namely the dynamics of the rhythmic applause. After a detailed experimental investigation, we describe the phenomenon with an approach based on the classical Kuramoto model ...
A.T. Winfree   +10 more
core   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

A High‐Performance Coupled Human And Natural Systems (CHANS) Model for Flood Risk Assessment and Reduction

open access: yesWater Resources Research
In recent years, flood risk in urban areas has been rapidly increasing due to unsustainable urban development, changes of hydrological processes and frequent occurrence of extreme weather events.
Haoyang Qin   +3 more
doaj   +1 more source

Layering for governance: Ecosystem service supply–demand trade-offs and social-ecological system network topologies from a cluster perspective

open access: yesEcological Indicators
A key challenge in ensuring the coordinated development of ecological conservation and economic growth is to gain a solid understanding of the interactions between supply–demand of ecosystem services (ES). However, empirical research on spatial imbalance
Linsheng Wen   +7 more
doaj   +1 more source

Launching the Grand Challenges for Ocean Conservation [PDF]

open access: yes, 2015
The ten most pressing Grand Challenges in Oceans Conservation were identified at the Oceans Big Think and described in a detailed working document:A Blue Revolution for Oceans: Reengineering Aquaculture for SustainabilityEnding and Recovering from Marine

core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

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