Results 191 to 200 of about 1,566,452 (319)

A fully coupled system of generalized thermoelastic theory for semiconductor medium. [PDF]

open access: yesSci Rep
Sherief H   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Dynamic response of vehicle-track coupling system with an insulated rail joint

open access: yes, 2013
The dynamic behavior of vehicle and track systems is studied in the presence of an insulated rail joint through a two-dimensional vehicle-track coupling model.
Grossoni, Ilaria   +3 more
core  

Analysis of multi-wave solitary solutions of (2+1)-dimensional coupled system of Boiti-Leon-Pempinelli. [PDF]

open access: yesSci Rep
Ghazanfar S   +7 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Lump, lump-periodic, lump-soliton and multi soliton solutions for the potential Kadomtsev-Petviashvili type coupled system with variable coefficients. [PDF]

open access: yesSci Rep
Chen H   +8 more
europepmc   +1 more source

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