Results 41 to 50 of about 163,068 (267)

Coupling Reactions

ChemInform, 2006
AbstractFor Abstract see ChemInform Abstract in Full Text.
Mecking, Stefan, Schlotterbeck, Ulf
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Coping Mechanisms of Previously Diagnosed and New HIV-Discordant, Heterosexual Couples Enrolled in a Pilot HIV Self-Testing Intervention Trial in Central Uganda

Frontiers in Reproductive Health, 2021
Introduction: Learning that a couple has HIV-discordant results can create tensions in the relationship including separation. We explored the coping mechanisms of HIV-discordant, heterosexual couples enrolled in an HIV self-testing (HIVST) intervention ...
Joseph K. B. Matovu, Joseph K. B. Matovu, Rose Kisa, Angela M. Malek, Caroline Vrana-Diaz, Semei Christopher Mukama, William Musoke, Jeffrey E. Korte, Rhoda K. Wanyenze   +8 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Dyadic Coping and Communication as Predictors of 10-Year Relationship Satisfaction Subgroup Trajectories in Stable Romantic Couples

Behavioral Sciences
Given the importance of relationship satisfaction and the detrimental effects of its decline in romantic couples, it is crucial to understand how relationship satisfaction develops over time in long-term stable relationships and to identify predictors ...
Michelle Roth, Fridtjof W. Nussbeck, Selina A. Landolt, Mirjam Senn, Thomas N. Bradbury, Katharina Weitkamp, Guy Bodenmann   +6 more
doaj   +1 more source

Couples Dealing With Pediatric Blood Cancer: A Study on the Role of Dyadic Coping

Frontiers in Psychology, 2019
Objective: Pediatric cancer is a life-threatening disease that poses significant challenges to the ill child and his/her parents. Among the studies investigating risk and protective factors for the individual and relationship adjustment of parents being ...
Marieke Van Schoors, Tom Loeys, Liesbet Goubert, Geertrui Berghmans, Britt Ooms, Jurgen Lemiere, Jurgen Lemiere, Koenraad Norga, Koenraad Norga, Lesley Liliane Verhofstadt   +9 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Couple Communication in Cancer: Protocol for a Multi-Method Examination

Frontiers in Psychology, 2022
Cancer and its treatment pose challenges that affect not only patients but also their significant others, including intimate partners. Accumulating evidence suggests that couples’ ability to communicate effectively plays a major role in the psychological
Shelby L. Langer, Joan M. Romano, Francis Keefe, Donald H. Baucom, Timothy Strauman, Karen L. Syrjala, Niall Bolger, John Burns, Jonathan B. Bricker, Jonathan B. Bricker, Michael Todd, Brian R. W. Baucom, Melanie S. Fischer, Neeta Ghosh, Julie Gralow, Veena Shankaran, S. Yousuf Zafar, Kelly Westbrook, Karena Leo, Katherine Ramos, Danielle M. Weber, Laura S. Porter   +21 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source