Results 41 to 50 of about 2,561,669 (294)
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Distress in couples coping with cancer: A meta-analysis and critical review of role and gender effects [PDF]
Research concerning distress in couples coping with cancer was integrated using meta-analysis and narrative critical appraisal. Individual levels of distress were determined more by gender than by the role of being the person with cancer versus that ...
Bolks, H.N. +10 more
core +2 more sources
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho +6 more
wiley +1 more source
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
What is behavioural couples’ therapy?
Behavioural couples’ therapy is one of two interventions (along with contingency management) highlighted as having ‘particularly strong evidence’ for effectiveness among people being treated for substance use problems.
Calder, Robert
core
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Effect of counselling and condom provision on sexual behaviour of heterosexual HIV discordant couples as part of an HIV prevention trial South Africa [PDF]
Includes abstract.Includes bibliographical references.South Africa as a country has a high HIV prevalence. Due to the fact that HIV transmission is predominantly heterosexual, HIV discordant couples are a high risk group for HIV.
Namale, Phiona Enid
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Patients with chronic diseases such as cancer are permanently worried about the progression or recurrence of their diseases. This fear of cancer spreading severely affects a patient’s quality of emotional and marital life.
Ali Zargaran, Masoumeh Hedayati
doaj +2 more sources

