Results 111 to 120 of about 23,458,446 (299)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Coupling time distribution asymptotics for some couplings of the Lévy stochastic area [PDF]

open access: yes, 2010
We exhibit some explicit co-adapted couplings for n-dimensional Brownian motion and all its Lévy stochastic areas. In the two-dimensional case we show how to derive exact asymptotics for the coupling time under various mixed coupling strategies, using
Kendall, W. S.
core  

Empirical analysis of phase-amplitude coupling approaches.

open access: yesPLoS ONE, 2019
Analysis of the coupling between the phases and amplitudes of oscillations within the same continuously sampled signal has provided interesting insights into the physiology of memory and other brain process, and, more recently, the pathophysiology of ...
Michael Caiola   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Numerically optimized Markovian coupling and mixing in one-dimensional maps [PDF]

open access: yes, 2007
Algorithms are introduced that produce optimal Markovian couplings for large finite-state-space discrete-time Markov chains with sparse transition matrices; these algorithms are applied to some toy models motivated by fluid-dynamical mixing problems at ...
P, D, Jansons, KMM
core  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Manufacturing Design and Predictive Maintenance Description of a Coupling

open access: yes
The main topics of the thesis was creating the 3D models of the coupling, methods of manufacturing and exploring predictive maintenance prospects for the coupling. 3D models were created by CAD software. DMG MORI NTX 2500 CNC machine was selected for its
Ahmed, Ahnaf Akif
core  

Construction Safety Risk Identification and Coupling Analysis Based on Data Mining

open access: yesBuildings
Frequent accidents in the construction sector arise from the dynamic coupling of multiple risk factors, while conventional single-factor approaches fail to capture the underlying complexity.
Guozong Zhang, Dexin Yang, Yuan Sun
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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