ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Analysis of Strategy for Energy Coupling Mechanism and Coordinated Control for Grid-Forming MMC with Dual Valve Groups [PDF]
[Objective] Grid-forming ultra-high voltage (UHV) flexible DC converter stations are a crucial solution for supporting the large-scale transmission of high-share renewable energy.
ZHAO Jiawen, HAN Minxiao, LU Wenze, XIONG Lingfei, FAN Linzhen
doaj +1 more source
Shunt power factor correction devices for damping of harmonic resonance in industrial power systems
THE PURPOSE. Harmonic resonance has become a serious problem of shunt capacitor banks for reactive power and voltage support. Effective solution to damp out the capacitor-caused resonance is the series connection of capacitor bank with harmonic damping ...
V. P. Dovgun +3 more
doaj +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
A Novel Compact Wideband Bandpass Filter With High Upper Stopband Rejection
This paper presents a novel compact wideband quadruple-mode bandpass filter (BPF) with four resonant modes and five transmission zeros (TZs). Two T-shaped stepped impedance stub loaded resonators are coupled in parallel to the input and output feed lines
Qijun Lu +4 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
A General Analysis of Passive Component Sizing for Current-Sourced Buck Converters
Power converter topologies with inductors at the input offer the potential to reduce conducted electromagnetic interference (EMI). To harness this benefit in converters conventionally implemented with inductors at the output, an input passive network ...
Qijia Li, Jonah Rawley, Samantha Coday
doaj +1 more source
A new capacitive coupler design for wireless capacitive power transfer applications
Capacitive power transfer (CPT) technology has become a promising alternative solution for wireless charging applications. This paper proposes a novel coupler design to form a resonant capacitor by inserting dielectric material between two bent metal ...
Mehmet Zahid Erel +2 more
doaj +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source

