Results 131 to 140 of about 4,155,600 (295)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Research on the coupling coordination and spatial relationship between the allocation of nursing human resources allocation and economic development level in China

open access: yesHuli yanjiu
ObjectiveTo explore the coupling coordination relationship and spatial distribution status between the nursing human resources allocation and the economic development level in China,and to provide reference basis for promoting the coordinated development
XIE Qian, XU Wen
doaj  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Study on the coupling and coordination relationship between health resource allocation and economic development level in Shanxi province

open access: yesHuli yanjiu
ObjectiveTo analyze the coupling and coordination degree and relative development degree of health resources and economic development in Shanxi province from 2017 to 2021, and to provide reference for promoting the coordinated development of health ...
WANG Xueyang, YAN Yingying, DUAN Zhaoxia
doaj  

Comprehensive index proportion and coupling coordination degree growth rate changes.

open access: yes
Comprehensive index proportion and coupling coordination degree growth rate changes.
Jingshan Gu (17817388)   +1 more
core   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Coupling and Coordinated Development Evaluation of Society-Ecology-Water Resources System in Central Yunnan

open access: yesRenmin Zhujiang
Exploring the coupling and coordination relationship among society, ecology, and water resources in central Yunnan is of significance to the sustainable development of central Yunnan and Yunnan.Based on emergy analysis and dual water resources ...
HE Guilin   +4 more
doaj  

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