Results 121 to 130 of about 17,148,895 (288)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The impact of the degree of coupling coordination between green finance and environmental regulations on firms’ innovation performance: evidence from China [PDF]

Integrating the resource-based view and institution-based view theories, this paper examines the impact of the degree of coupling coordination between green finance and environmental regulations on firms’ innovation performance.
Sun, Zhennan, Du, Min, Yang, Tianle, Du, Qunyang, Li, Lei, Shuwaikh, Fatima   +5 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Research on the Coupling Relationship between Retail Commercial Space and Metro Stations in Xiamen City Based on POI Data

Chengshi guidao jiaotong yanjiu
ObjectiveThe commercial development around subway stations is increasingly linked to subway lines. Studying the coupling between the two is of great significance for optimizing urban commercial layout and traffic planning. MethodA total of 77 stations in
Lixie SU, Sisheng YANG
doaj   +1 more source

Agricultural Technology Innovation and Food Security in China: An Empirical Study on Coupling Coordination and Its Influencing Factors

Agronomy
The coupling coordination of agricultural technology innovation with food security is of great significance for high-quality agricultural development.
Chuansong Zhao, Ran Geng, Tianhao Chi, Chatchai Khiewngamdee, Jianxu Liu   +4 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

The spatio-temporal characteristics and dynamic evolution of coupling and coordinated development of innovation factor allocation and green economy in China

Frontiers in Environmental Science
IntroductionMeasuring the coupling coordination degree between the innovation factor allocation system and the green economy development system, and deeply exploring the changing trends in the coupling coordination between innovation factors allocation ...
Kangshun Geng, Xiaotao Zhang, Hong Jiang, Zixuan Zhuang   +3 more
doaj   +1 more source

Coupling coordination degree of national fitness and national health.

Coupling coordination degree of national fitness and national health.
Dongxu Lin (207963), Lin Niu (456354), Jinfu Xu (8194992), Haixia Wang (173360)   +3 more
core   +1 more source