Results 51 to 60 of about 299,628 (304)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Optimization of space laser coupling with few-mode fiber in the presence of random angular jitter
AIP Advances, 2022 In a space laser communication system with a few-mode fiber as the receiving terminal, the influence of random angular jitter on the communication performance cannot be ignored.
Zhaoyuan Zhang
doaj +1 more source
Energy Strategy Reviews, 2022 This paper first estimates the energy efficiency of 13 cities and 30 key industries in the Beijing-Tianjin-Hebei (BTH) region between 2008 and 2017 using the super-efficiency slacks-based measure (SBM) model.
Liming Xue +6 more
doaj +1 more source
Limits of coupling efficiency into hollow-core antiresonant fibres
, 2023 We theoretically explore the fundamental limits on the efficiency of coupling light into hollow-core antiresonant fibres. We study in particular the coupling of a free-space Gaussian beam to the guided modes of one of the most successful antiresonant ...
Mulvad, Hans Christian H. +6 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
More efficient second harmonic generation of whispering gallery modes by selective out-coupling
, 2017 We demonstrate second harmonic generation (SHG) in an $x$-cut congruent lithium niobate (LN) whispering gallery mode resonator. We first show theoretically that independent control of the coupling of the pump and signal modes is optimal for high ...
Florian Sedlmeir (16512354) +3 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Scientific Reports, 2023 The spatial differences of efficiency and development level of regional tourism are evident, and the dynamic grasp of their spatiotemporal evolution characteristics and coupling coordination relationship is important to promote high-quality sustainable ...
Zhenjie Liao, Lijuan Zhang, Shan Liang
doaj +1 more source