Results 71 to 80 of about 6,778,426 (314)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Analysis of Thermoelastic Coupling Vibration of Friction Plate in Friction Clutch

open access: yesJixie chuandong, 2019
Based on thin plate theory and thermal conduction equation in view of deformation effect, the thermoelastic coupling model of annular plate and the corresponding motion differential equation of friction plate in the friction clutch is established.
Yongqiang Yang   +2 more
doaj  

Experiments of opening and cavity shear flow-induced vibration and structural coupling resonance

open access: yesZhongguo Jianchuan Yanjiu, 2017
In order to discuss opening and cavity shear flow-induced vibration and structural coupling resonance, experiments of opening and cavity shear flow-induced vibration and structural noise control are carried out.
XIONG Jishi   +4 more
doaj   +1 more source

Spin structure factors of doped monolayer Germanene in the presence of spin-orbit coupling

open access: yesScientific Reports, 2021
In this paper, we present a Kane-Mele model in the presence of magnetic field and next nearest neighbors hopping amplitudes for investigations of the spin susceptibilities of Germanene layer.
Farshad Azizi, Hamed Rezania
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Frequency shifted polaron coupling in GaInAs heterostructures

open access: yesSurface Science Letters, 1986
Abstract Frequency dependent cyclotron resonance measurements are reported on Ga0.47In0.53AsInP and Ga0.47In0.53AsAl0.48In0.52As heterostructures. Discontinuities in the effective mass are observed at two frequencies, due to resonant polaron coupling to the two optic phonon modes in GaInAs.
Brunel, L   +9 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Phase-amplitude coupling at the organism level: The amplitude of spontaneous alpha rhythm fluctuations varies with the phase of the infra-slow gastric basal rhythm

open access: yesNeuroImage, 2017
A fundamental feature of the temporal organization of neural activity is phase‐amplitude coupling between brain rhythms at different frequencies, where the amplitude of a higher frequency varies according to the phase of a lower frequency.
Craig G. Richter   +3 more
semanticscholar   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Brain Functional Connectivity Through Phase Coupling of Neuronal Oscillations: A Perspective From Magnetoencephalography

open access: yesFrontiers in Neuroscience, 2019
Magnetoencephalography has gained an increasing importance in systems neuroscience thanks to the possibility it offers of unraveling brain networks at time-scales relevant to behavior, i.e., frequencies in the 1–100 Hz range, with sufficient spatial ...
L. Marzetti   +5 more
semanticscholar   +1 more source

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