Redirecting the Peptide Cleavage Causes Protease Inactivation
Cysteine and serine proteases cleave peptides through covalent catalysis by generating a transient adduct with the N‐terminal part of the substrate after releasing its C‐terminal part. We demonstrate the unique redirection of this event leading to strong enzyme inactivation.
Michael Gütschow+20 more
wiley +1 more source
Spinel‐Layered Heterostructure Enables Reversible Oxygen Redox in Lithium Manganese Oxide
Lithium‐rich manganese‐based layered oxides (LRMOs) have emerged as promising cathode materials for next‐generation lithium‐ion batteries (LIBs), primarily due to their exceptional capacity originating from oxygen redox chemistry. While Li2MnO3 (LMO) has been conventionally identified as the oxygen redox‐active component in LRMOs, this layered material
Yanfang Wang+13 more
wiley +1 more source
An Investigation on the Ball Screw-Based Variable Displacement Mechanism for Axial Piston Pumps with Feedforward Differential Input Control. [PDF]
Zhang G, Wang B, Lin YJ.
europepmc +1 more source
ABSTRACT Chemical facilities storing large volumes of flammable liquids close to residential areas pose severe fire‐and‐explosion hazards that can escalate into disasters. In this study, a tank farm located within Istanbul's city limits is examined to evaluate possible catastrophic scenarios using consequence analysis methods. For this purpose, several
Tahsin Aykan Kepekli
wiley +1 more source
Experimental results of a 330 GW impedance-matched Marx generator. [PDF]
Damideh V+20 more
europepmc +1 more source
ABSTRACT Flexible high‐performance electronics are facing the challenge of managing increasing thermal loads in the latest devices. This study presents a one‐step method for 3D printing flexible boron nitride (BN) polymer composites via vat photopolymerization, enhancing thermal conductivity by 270% to 0.8 W m−1 K−1 and improving dielectric properties (
Simone Bagatella+5 more
wiley +1 more source
Bearing characteristics and continuous-discontinuous numerical analysis of a pressure grouting pile in a calcareous sand foundation. [PDF]
Cheng Q+5 more
europepmc +1 more source
Advances in Chlorinated Polyethylene: Properties, Applications, and Future Directions
This work highlights recent advances in the synthesis of chlorinated polyethylene (CPE), its versatile industrial applications, and emerging innovations driving its future development in sustainable materials. ABSTRACT Elastomeric chlorinated polyethylene (CM or E‐CPE) integrates the thermoplastic's dynamic processing properties with the elastomer's ...
J. I. Mnyango+7 more
wiley +1 more source
Sharpening our understanding of saber‐tooth biomechanics
Abstract Saber‐teeth are a striking example of convergent evolution in vertebrate predators, having evolved multiple times in mammals and their early ancestors. While there is broad consensus that saber‐toothed taxa employed a distinct biting strategy compared to conical‐toothed carnivores, like the lion, the precise mechanics and variability of this ...
Tahlia Pollock, Philip S. L. Anderson
wiley +1 more source
Techno-Economic Assessment of Atmospheric Carbon Removal via Industrial Composting of Biomass Waste with CO <sub><b>2</b></sub> Capture. [PDF]
Woods E+3 more
europepmc +1 more source