Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Impact of a Practical, Hands-On, Continuing Professional Development Course About AI in Health Care Professions Education on the Perceptions and Behaviors of Health Care Educators: Qualitative Case Study. [PDF]
JMIR Med EducPeacock JG, Merkebu J, Samuel A.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Applying social entrepreneurship to One Health and climate education: a retrospective analysis of pre- and post-course survey data for a One Health and Global Food Security course. [PDF]
Front Vet SciParsons B, Watson B.
europepmc +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Implementation of a portfolio assignment in the framework of an internship in dental higher education with a focus on preventive dentistry. [PDF]
BMC Med EducHofmann M, Krebs N, Krämer N.
europepmc +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Cadaver-based hands-on course in cervical spine surgery: a prospective evaluation of surgical confidence and self-perceived autonomy. [PDF]
Acta Neurochir (Wien)Alakmeh A +5 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Development of a Web-Based Intervention Course to Promote Academic Staff Well-Being: Protocol for a Mixed Methods Study Design. [PDF]
JMIR Res ProtocAsikainen H, Lampinen V, Katajavuori N.
europepmc +1 more source