Results 71 to 80 of about 3,068,177 (243)
Game accessibility course design modules in higher education
Frontiers in Computer ScienceGame accessibility has evolved significantly during the last 10 years, both within the industry and in research. Further inclusion in both games and the game industry requires educational resources useful within game curricula, which has been developed ...
Thomas Westin
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
FEBS Letters, EarlyView.The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Revista Facultad de Odontología Universidad de Antioquia, 1998 The curricular and administrative components were considered in one articule because the two form an unity. In the curricula was analized the general objectives, study plans, courses, contents, methods, evaluation and programs.
Nury Ossa-de D. +1 more
doaj
Early juvenile arthritis – results of two-year follow up
Научно-практическая ревматология, 2009 Objective. To study clinical and laboratory manifestations of different variants of juvenile arthritis (JA) at the disease onset and during prospective two-year follow up. Material and methods.
S O Salugina +3 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Artuklu HumanitiesBu çalışmanın amacı ilkokul ve ortaokul süresince öğrencilerin aldıkları önemli derslerden biri olan sosyal bilgiler dersi ve bu dersi veren öğretmenler hakkındaki zihinsel deneyimlerini ortaya çıkarmaktır.
Erhan Görmez, Atilla Keser
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source