Results 111 to 120 of about 1,516,828 (318)

ORF6, a repressor of the MHC class I pathway: new molecular target for SARS-CoV-2 drug discovery? [PDF]

open access: bronze, 2023
Baohui Zhu   +3 more
openalex   +1 more source

Cicho\'n's maximum

open access: yes, 2019
Assuming four strongly compact cardinals, it is consistent that all entries in Cicho\'n's diagram are pairwise different, more specifically that \[ \aleph_1 < \mathrm{add}(\mathrm{null}) < \mathrm{cov}(\mathrm{null}) < \mathfrak{b} < \mathrm{non}(\mathrm{
Goldstern, Martin   +2 more
core   +2 more sources

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi   +2 more
wiley   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

open access: yesAdvanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram   +10 more
wiley   +1 more source

SARS-CoV-2 surveillance in a hospital and control of an outbreak on a geriatric ward using whole genome sequencing

open access: yesInfection Prevention in Practice
Summary: Background: During the SARS-CoV-2 pandemic, dominant viral variants were repeatedly replaced by new variants with altered properties, frequently changing the dynamics of the infection event, as well as the effectiveness of vaccines and ...
Hanno Schmidt   +11 more
doaj   +1 more source

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini   +2 more
wiley   +1 more source

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

open access: yesAdvanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich   +8 more
wiley   +1 more source

Duality and the pcf theory

open access: yes, 2002
We consider natural cardinal invariants hm_n and prove several duality theorems, saying roughly: if I is a suitably definable ideal and provably cov(I)>=hm_n, then non(I) is provably small.
Shelah, Saharon, Zapletal, Jindrich
core   +1 more source

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