Results 181 to 190 of about 1,516,828 (318)

Automatically Defining Protein Words for Diverse Functional Predictions Based on Attention Analysis of a Protein Language Model

Advanced Science, EarlyView.
Understanding protein sequence–function relationships remains challenging due to poorly defined motifs and limited residue‐level annotations. An annotation‐agnostic framework is introduced that segments protein sequences into “protein words” using attention patterns from protein language models.
Hedi Chen, Jingrui Zhong, Xiaochun Zhang, Jingke Chen, Lin Guo, Xiaoliang Xiong, Xiaonan Zhang, Xiangyu Liu, Bailong Xiao, Boxue Tian   +9 more
wiley   +1 more source

Raw diffraction data for structure of SARS-CoV-2 main protease with Z1367324110 (ID: mpro-x0195 / PDB: 5R81)

, 2020
David Aragão, J. Brandão-Neto, Anna Carbery, Adam Crawshaw, Alexandre Dias, A. Douangamath, Louise Dunnett, D. Fearon, Ralf Flaig, Paul Gehrtz, Dave Hall, T. Krojer, Nir London, Petra Lukacik, Marco Mazzorana, Katherine McAuley, David Owen, A.J. Powell, Rambabu Reddi, Efrat Resnick, R. Skyner, Matt Snee, Claire Strain‐Damerell, David I. Stuart, F. von Delft, Martin Walsh, Conor Wild, Mark Williams, Graeme Winter   +28 more
openalex   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

Corrigendum: Analysis of a super-transmission of SARS-CoV-2 omicron variant BA.5.2 in the outdoor night market [PDF]

, 2023
Mingyu Luo, Shelan Liu, Liebo Zhu, Fengying Wang, Kunyang Wu, Hanqing He, Xiaohua Qi, Zhifeng Pang, Xuanjun Dong, Zhenyu Gong, Min Yu   +10 more
openalex   +1 more source

Design and Optimization of Full‐Stokes Hyperspectro‐Polarimetric Encoding Metasurfaces Based on Conditional Multi‐Task Deep Learning

Advanced Science, EarlyView.
A conditional multi‐task deep learning framework is developed for designing and optimizing Full‐Stokes Hyperspectro‐Polarimetric Encoding Metasurfaces (FHPEMs). This framework achieves joint spectro‐polarimetric learning and unified forward–inverse design.
Chenjie Gong, Haodong Shi, Qi Wang, Yingchao Li, Hongyu Sun, Jiayu Wang, Guanlin Li, Jian Zhang, Qiang Fu, Huilin Jiang   +9 more
wiley   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Raw diffraction data for structure of SARS-CoV-2 main protease with Z1741970824 (ID: mpro-x0995 / PDB: 5RF3)

, 2020
David Aragão, J. Brandão-Neto, Anna Carbery, Adam Crawshaw, Alexandre Dias, A. Douangamath, Louise Dunnett, D. Fearon, Ralf Flaig, Paul Gehrtz, Dave Hall, T. Krojer, Nir London, Petra Lukacik, Marco Mazzorana, Katherine McAuley, David Owen, A.J. Powell, Rambabu Reddi, Efrat Resnick, R. Skyner, Matt Snee, Claire Strain‐Damerell, David I. Stuart, F. von Delft, Martin Walsh, Conor Wild, Mark Williams, Graeme Winter   +28 more
openalex   +1 more source

AP‐Lab: An AI‐Driven Autonomous Pilot‐Scale Platform Bridging Materials Discovery and Industrial Manufacturing

Advanced Science, EarlyView.
AP‐Lab bridges materials discovery and industrial manufacturing by coupling proprietary datasets with an application benchmark (PCR Ct). A closed‐loop optimization workflow integrates ML, LLM, and autonomous synthesis/testing to refine magnetic nanoparticles–based nucleic‐acid extraction systems.
Zhan‐Long Wang, Zhifen Ma, Wenxing Song, Guolai Jiang, Boshi Jiang, Mingyang Jiang, Weiliang Shu, Bing Wang, Zhiyuan Wan, Shengyong Geng, Zhen Zhao, Wenhua Zhou, Xue‐Feng Yu   +12 more
wiley   +1 more source

TopCas: Topology‐Gated Cas12a via DNA‐RNA Chimeric Circular crRNA for Amplification‐Free Nucleic Acid Detection and Conditional Gene Editing

Advanced Science, EarlyView.
The TopCas platform utilizes an engineered DNA‐RNA chimeric circular crRNA to establish topology‐gated control over CRISPR‐Cas12a activity, enabling target‐triggered self‐catalytic amplification (preamplification‐free). This system seamlessly integrates highly sensitive molecular diagnostics with conditionally controlled gene editing, demonstrating ...
Shun Zhang, Wen Sun, Ting Xiao, Yali Wang, Xianlan Wu, Huiyou Chen, Ming Chen, Jun Zhang   +7 more
wiley   +1 more source

Wood‐Based Bioelectronics: Lignosulfonate‐Based Conductive Biocomposites for Paper Organic Electrochemical Transistors

Advanced Electronic Materials, EarlyView.
Biodegradable wood‐based bioelectronics are realized by integrating poly (2,3‐ethylenedioxythiopene:lignosulfonate (PEDOT:LigS) as a mixed ionicelectronic channel in organic electrochemical transistors fabricated on paper substrates. The biocomposite exhibits high conductivity, biocompatibility, and strong transistor performance, while devices built on
Katharina Matura, Tobias Grabner, Sarka Hradilova, Munise Cobet, Ariana Opletalova, Katerina Polakova, Alessandra Operamolla, Niyazi Serdar Sariciftci, Serpil Tekoglu   +8 more
wiley   +1 more source