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Correction for Te et al., Broad beta-CoV immunity and transmission blockade by a single-dose live-attenuated vaccine with atypical codon usage. [PDF]
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2021
AbstractThe emergence of the novel SARS-CoV-2 in 2019 sparked a dispute concerning its origin. Here, we report that the SARS-CoV-2 originated through pangolin-coronavirus (Pan-CoVs) from the SARS-CoV-related-bat-coronaviruses (SARS-CoV-1-rB-CoVs) rather than from SARS-CoV-2-related-bat-coronaviruses (SARS-CoV-2-rB-CoVs), in contrast to the previous ...
Perumal Arumugam Desingu, K. Nagarajan
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AbstractThe emergence of the novel SARS-CoV-2 in 2019 sparked a dispute concerning its origin. Here, we report that the SARS-CoV-2 originated through pangolin-coronavirus (Pan-CoVs) from the SARS-CoV-related-bat-coronaviruses (SARS-CoV-1-rB-CoVs) rather than from SARS-CoV-2-related-bat-coronaviruses (SARS-CoV-2-rB-CoVs), in contrast to the previous ...
Perumal Arumugam Desingu, K. Nagarajan
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Fangchinoline inhibits SARS-CoV-2 and MERS-CoV entry
Antiviral Research, 2023The COVID-19 pandemic caused by SARS-CoV-2, lead to mild to severe respiratory illness and resulted in 6.9 million deaths worldwide. Although vaccines are effective in preventing COVID-19, they may not be sufficient to protect immunocompromised individuals from this respiratory illness. Moreover, novel emerging variants of SARS-CoV-2 pose a risk of new
Srikanth Sadhu +17 more
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Diversity in the Accessory Proteins of SARS-CoV-2, SARS-CoV, and MERS-CoV Betacoronaviruses
Current Protein & Peptide Science, 2021: Along with structural and non-structural proteins, SARS-CoV-2, SARS-CoV, and MERS-CoV can also express accessory proteins. During the past few years, there have been only a few studies focusing on this set of proteins. Despite available data on these proteins, there are still a lot of questions on the functions of these proteins during infection ...
Christian A.K. Cruz, Paul M.B. Medina
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SARS‐CoV‐2, SARS‐CoV, and MERS‐CoV encode circular RNAs of spliceosome‐independent origin
Journal of Medical Virology, 2022Abstract Circular RNAs (circRNAs) are a newly recognized component of the transcriptome with critical roles in autoimmune diseases and viral pathogenesis. To address the importance of circRNA in RNA viral transcriptome, we systematically identified and characterized circRNAs encoded by the RNA genomes of betacoronaviruses using both ...
Shaomin Yang +15 more
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Coronaviruses (including SARS CoV and MERS CoV)
2016This chapter discusses coronaviruses. These infect humans, birds, and other animals. The first two human strains identified infect the respiratory tract and are normally confined to the ciliary epithelium of the trachea, nasal mucosa, and alveolar cells of the lungs. The chapter points out that the typical symptom of the coronavirus is the common cold
John Oxford, Paul Kellam, Leslie Collier
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