Results 51 to 60 of about 299,162 (292)
Covalent bonds in positron dihalides
Chemical Science, 2020 We report a computational study on homo- and heteronuclear e+[X−Y−] compounds formed by two halide anions (X−, Y−= F−, Cl−, Br−) and one positron.
Félix Moncada +4 more
openaire +4 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Functional Supramolecular Architectures of Dipyrrin Complexes
Frontiers in Chemistry, 2018 Dynamic formation of self-assemblies from molecular components is a useful and efficient way to produce molecular and supramolecular architectures with sophisticated functions.
Ryota Matsuoka, Tatsuya Nabeshima
doaj +1 more source
Molecules, 2023 A novel hydrogen bond surrogate-based (HBS) α-helix mimetic was designed by the combination of covalent H-bond replacement and the use of an ether linkage to substitute an amide bond within a short peptide sequence. The new helix template could be placed
Junyang Liu +3 more
doaj +1 more source
Energy Threshold for D+H_2→DH+H Reaction [PDF]
, 1966 We have been able to measure the threshold energy Eo for the reaction D+H_2→DH+H. The value obtained was (0.33±0.02) eV. Apparently, this is the first direct determination of a threshold energy for a reaction involving the ...
Kuppermann, Aron, White, John M.
core
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Nature CommunicationsOrganic molecules with dynamic covalent-bonding characteristics have attracted much attention for their important role in constructing stimulus-responsive smart materials.
Yuanshan Huang +5 more
doaj +1 more source
The Additivity of the Energies of Normal Covalent Bonds [PDF]
, 1932 The chemical bond between two identical atoms, as in the molecules H2, Cl2, etc., may be considered as an example of a normal covalent bond, involving an electron pair shared by the two atoms.
Pauling, Linus, Yost, Don M.
core
, 2011 Hydrogen produced from the photocatalytic splitting of water is one of the reliable alternatives to replace the polluting fossil and the radioactive nuclear fuels.
Arulsamy, Andrew Das +4 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source