Results 211 to 220 of about 390,156 (271)

Shifting the PPARγ conformational ensemble toward a transcriptionally repressive state improves covalent inhibitor efficacy. [PDF]

Elife
Arifova L, MacTavish BS, Laughlin Z, Karadi Girdhar MN, Shang J, Li MH, Yu X, Zhu D, Kamenecka TM, Kojetin DJ.   +9 more
europepmc   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Site-Selective Ligand Selection by Mutational Profiling for Covalent RNA Targeting. [PDF]

Angew Chem Int Ed Engl
Yesley P, Poulladofonou G, Incarnato D, Velema WA.   +3 more
europepmc   +1 more source

Electrochemically Driven Dissipative Growth of Affinity Hydrogels for Bioresponsive Interfaces

Advanced Functional Materials, EarlyView.
Voltage pulses drive the growth and reinforcement of hydrogel films under dissipative conditions. This biocompatible strategy enables efficient integration of affinity ligands into the hydrogel matrix, enhancing the selective capture of growth factors and allowing precise temporal control over their release, making them well‐suited as adaptive ...
Roberto Baretta, Marco Frasconi
wiley   +1 more source

Non-Covalent Interactions in Organocatalysis

, 2014
openaire   +2 more sources

Robust and Reversible Thermofluorescence in Solvent‐Free Thermoplastic Polyurethane Composites

Advanced Functional Materials, EarlyView.
Thermofluorescent polymer composites with high‐contrast optical outputs are prepared by solvent‐free blending of indenoquinacridone dye into a thermoplastic polyurethane matrix. The temperature‐dependent fluorescence originates from aggregation–dissociation of the dye molecules, regulated by competing hydrogen bonds from the polymer matrix.
Guanghua Yu, Bowen Tian, Jazmine Aiya Marquez, Chia‐Min Hsieh, Qingsheng Wang, Hung‐Jue Sue, Mohammed Al‐Hashimi, Peiran Wei, Lei Fang   +8 more
wiley   +1 more source

Recent Insights into Protein-Polyphenol Complexes: Molecular Mechanisms, Processing Technologies, Synergistic Bioactivities, and Food Applications. [PDF]

Molecules
Huynh HD, Thi THT, Thi TXT, Nargotra P, Wang HD, Liu YC, Kuo CH.   +6 more
europepmc   +1 more source

Impact of Surface Functionalization on NV Quantum Properties: Implications for Biosensing with Fluorescent Nanodiamonds

Advanced Functional Materials, EarlyView.
Fluorescent nanodiamonds (fNDs) have emerged as an invaluable quantum sensing platform for biological and biochemical systems. This paper investigates the influence of common surface functionalization strategies for bioconjugation on the quantum properties of nitrogen vacancy (NV) centers in nanodiamonds.
Anja Sadžak, Iván Pérez, Mateja Guimarães, Lukas Spantzel, Fedor Jelezko, Michael Börsch, Anke Krueger   +6 more
wiley   +1 more source

Protein structural dynamics in covalent drug design: insights from irreversible and reversible covalent inhibitors. [PDF]

RSC Chem Biol
Basu R, Fletcher S.
europepmc   +1 more source

Controlled Movement of Soft Actuators using Multi‐Responsive Microgel Arrays and Microcirculatory Systems

Advanced Functional Materials, EarlyView.
Microscale hydrogels (microgels) feature improved mass transport characteristics supportive of fast actuation and chemical tunability amenable to programmed stimuli response. A unique soft actuator architecture is realized by encapsulating microgels in soft microcirculatory systems which enable the convenient delivery of liquid stimuli for powering and
Nengjian Huang, Brennan P. Watts, Stephen A. Morin   +2 more
wiley   +1 more source