Results 61 to 70 of about 531,665 (271)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Model Risk in Portfolio Optimization
Risks, 2014 We consider a one-period portfolio optimization problem under model uncertainty. For this purpose, we introduce a measure of model risk. We derive analytical results for this measure of model risk in the mean-variance problem assuming we have ...
David Stefanovits +2 more
doaj +1 more source
IEEE Access, 2020 The estimation of the large and high-dimensional covariance matrix and precision matrix is a fundamental problem in modern multivariate analysis. It has been widely applied in economics, finance, biology, social networks and health sciences. However, the
Xin Yuan +3 more
doaj +1 more source
When do improved covariance matrix estimators enhance portfolio optimization? An empirical comparative study of nine estimators [PDF]
, 2010 The use of improved covariance matrix estimators as an alternative to the sample estimator is considered an important approach for enhancing portfolio optimization.
Lillo, Fabrizio +3 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
SGA based symbol detection and EM channel estimation for MIMO systems [PDF]
, 2006 This paper investigates iterative channel estimation and symbol detection for spatial multiplexing multiple input multiple output (MIMO) systems with frequency flat block fading channels using the expectation-maximization (EM) algorithm.
Andrieu, Christophe +3 more
core +2 more sources
Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial
Arthritis Care &Research, EarlyView.Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham +29 more
wiley +1 more source
DOA Estimation of Completely Polarized Signals by One-Bit Cross-Dipole Arrays
IEEE AccessThe one-bit cross-dipole array employs one-bit quantization to reduce the sampling system overhead while extracting polarization information from electromagnetic signals, thereby lowering the system complexity of the polarization array.
Yu Wang +5 more
doaj +1 more source
Cholesky-based model averaging for covariance matrix estimation
Statistical Theory and Related Fields, 2017 Estimation of large covariance matrices is of great importance in multivariate analysis. The modified Cholesky decomposition is a commonly used technique in covariance matrix estimation given a specific order of variables.
Hao Zheng +3 more
doaj +1 more source