Results 31 to 40 of about 309,621 (292)
Paired outcomes are common in correlated clustered data where the main aim is to compare the distributions of the outcomes in a pair. In such clustered paired data, informative cluster sizes can occur when the number of pairs in a cluster (i.e., a ...
Sandipan Dutta
doaj +1 more source
Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis +9 more
wiley +1 more source
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis +13 more
wiley +1 more source
On tests of treatment-covariate interactions: An illustration of appropriate power and sample size calculations. [PDF]
The appraisals of treatment-covariate interaction have theoretical and substantial implications in all scientific fields. Methodologically, the detection of interaction between categorical treatment levels and continuous covariate variables is analogous ...
Gwowen Shieh
doaj +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Understanding covariate shift in model performance [version 3; referees: 2 approved]
Three (3) different methods (logistic regression, covariate shift and k-NN) were applied to five (5) internal datasets and one (1) external, publically available dataset where covariate shift existed.
Georgia McGaughey +2 more
doaj +1 more source
An Efficient Gait Recognition Method for Known and Unknown Covariate Conditions
Gait is a unique non-invasive biometric form that can be utilized to effectively recognize persons, even when they prove to be uncooperative. Computer-aided gait recognition systems usually use image sequences without considering covariates like clothing
Maryam Bukhari +7 more
doaj +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Rapid urbanization urges the immediate attention of policymakers to ensure sustainable city development. Understanding the urban growth drivers is essential to address effective strategies for urbanization-related challenges.
Tirthankar Basu +2 more
doaj +1 more source

