Results 61 to 70 of about 540,575 (323)
CSF Biomarker‐Based Cognitive Trajectories in Parkinson's Disease‐Subjective Cognitive Decline
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive complaints without objective cognitive impairment in Parkinson's Disease, termed Parkinson's Disease‐Subjective Cognitive Decline (PD‐SCD), have been associated with cognitive decline. However, its progression is heterogeneous, highlighting the need for improved identification of patients at greater risk for deterioration ...
Jon Rodriguez‐Antiguedad +7 more
wiley +1 more source
The Importance of Scale for Spatial-Confounding Bias and Precision of Spatial Regression Estimators [PDF]
, 2009 Residuals in regression models are often spatially correlated. Prominent examples include studies in environmental epidemiology to understand the chronic health effects of pollutants.
Paciorek, Christopher J.
core +3 more sources
An Analysis for IDH‐Mutant Grade 4 Astrocytoma Based on WHO CNS 5: Implication of Clinical Practice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose There is ongoing debate regarding the therapeutic approach and prognosis for IDH‐mutant grade 4 astrocytoma, a newly defined subtype of diffuse glioma in the 2021 WHO classification system for central nervous system tumors (WHO CNS 5). The aim of this study was to explore the clinical outcome and prognosticators for newly diagnosed IDH‐
Xianxin Qiu +13 more
wiley +1 more source
Randomization Tests that Condition on Non-Categorical Covariate Balance
Journal of Causal Inference, 2019 A benefit of randomized experiments is that covariate distributions of treatment and control groups are balanced on average, resulting in simple unbiased estimators for treatment effects.
Branson Zach, Miratrix Luke W.
doaj +1 more source
A Simple Test for the Absence of Covariate Dependence in Hazard Regression Models [PDF]
, 2004 This paper extends commonly used tests for equality of hazard rates in a two-sample or k-sample setup to a situation where the covariate under study is continuous.
Bhattacharjee, Arnab
core +4 more sources
, 2011 Motivated by a potential-outcomes perspective, the idea of principal stratification has been widely recognized for its relevance in settings susceptible to posttreatment selection bias such as randomized clinical trials where treatment received can ...
Belin, Thomas R., Zigler, Corwin M.
core +1 more source
Ambivalent covariance models [PDF]
BMC Bioinformatics, 2015 Evolutionary variations let us define a set of similar nucleic acid sequences as a family if these different molecules execute a common function. Capturing their sequence variation by using e. g. position specific scoring matrices significantly improves sensitivity of detection tools.
Janssen, Stefan, Giegerich, Robert
openaire +3 more sources
EEG Response to Sedation Interruption Complements Behavioral Assessment After Severe Brain Injury
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Accurate assessment of the level of consciousness and potential to recover in patients with severe brain injury underpins crucial decisions in the intensive care unit but remains a major challenge for the clinical team. The neurological wake‐up test is a widely used assessment tool. However, many patients' behavioral responses during
Charlotte Maschke +12 more
wiley +1 more source
Inference after covariate-adaptive randomisation: aspects of methodology and theory
Statistical Theory and Related Fields, 2021 Covariate-adaptive randomisation has a more than 45 years of history of applications in clinical trials, in order to balance treatment assignments across prognostic factors that may have influence on the outcomes of interest.
Jun Shao
doaj +1 more source
Covariate assisted screening and estimation
, 2014 Consider a linear model $Y=X\beta+z$, where $X=X_{n,p}$ and $z\sim N(0,I_n)$. The vector $\beta$ is unknown but is sparse in the sense that most of its coordinates are $0$. The main interest is to separate its nonzero coordinates from the zero ones (i.e.,
Fan, Jianqing +2 more
core +1 more source